Autoantibodies to angiotensin-converting enzyme 2 in patients with connective tissue diseases

Table 1 Patient demographics

Parameter	Vasculopathy patients	Control patients
Number of patients	18 (17 females, 1 male)	24 (21 females, 3 males)
Age (years)	50.5 ± 14.3	46.8 ± 17.8
Disease entities	SLE (4), SSc (6), MCTD (8)	SLE (21), SSc (2), MCTD (1)
Constrictive vasculopathies	PAH (5); all patients had SSc^a; persistent digital ischemia (16)	None

Data presented as n or mean ± standard deviation. PAH, pulmonary arterial hypertension; MCTD, mixed connective tissue disease; SLE, systemic lupus erythematosus; SSc, systemic sclerosis. ^aThree patients also had digital ulcers; of these, one patient had a history of scleroderma renal crisis.

ISSN: 1478-6362