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Table 1 Histological score and osteoclast number

From: Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice

 

Synovium

Leukocyte

Cartilage/bone

Osteoclast

Vehicle (n = 6)

2.3 ± 0.8

1.7 ± 0.9

2.7 ± 0.6

62.0 ± 38.6

ZSTK474

(n = 6, 50 mg/kg)

0.0 ± 0.0

0.0 ± 0.0

0.8 ± 0.3

0.3 ± 0.2

P-value

0.009

0.073

0.036

0.024

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Arthritis Research & Therapy

ISSN: 1478-6362

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