Figure 2From: The use of glucocorticoids in rheumatoid arthritis - no 'rational' approach yetThe direct and indirect effects of glucocorticoids on bone leading to glucocorticoid-induced osteoporosis and fractures. Figure obtained with permission from [4]. CSF, colony stimulating factor; GH, growth hormone; IGF, insulin-like growth factor; RANKL, Receptor activator of nuclear factor-kappa B ligand. The full colour version of this fi gure is available online at http://arthritis-research.com/content/12/3/127Back to article page