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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Optical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritis

Figure 1

Disease incidence, clinical score, and paw thickness readouts of treated and untreated CAIA mic. (a) Disease incidence in control and treated collagen antibody-induced arthritis (CAIA) mice (n = 12 mice per group), defined as any animal showing a clinical score ≥1 in at least one paw. (b) Average clinical score values of all paws for control and treated CAIA mice (n = 12 mice per group). (c) Average changes in paw thickness from day 4 to day 8 for control and treated CAIA mice. Study is representative of three separate experiments. #P < 0.05, ***P < 0.0001.

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