Immediate (seconds) | Acute (months) | Chronic (years) |
---|---|---|
Cell necrosis | Apoptosis | Joint tissue remodeling |
Collagen rupture | Leukocyte infiltration | Â |
Glycosaminoglycan loss | Inflammatory mediators | Â |
Hemarthrosis | Extracellular matrix degradation | Inflammation |
 | Deficient lubricants |  |
 | Arthrofibrosis |  |