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Table 1 Basic characteristics of patients with RA and control subjects*

From: Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study

  Controls
(n = 1,004)
RA cases
(n = 1,313)
anti-CCP-positive RA
(n = 822)
anti-CCP-negative RA
(n = 145)
Female, No. (%) 864 (86.1) 1,170 (89.1) 734 (89.3) 128 (88.3)
Age (mean ± SD years) 36.7 ± 12.5 51.8 ± 12.2 51.7 ± 11.8 50.5 ± 11.3
Onset age (mean ± SD years) - 40.6 ± 12.4 40.5 ± 12.1 38.5 ± 11.9
Ever-smokers, No. (%) 134 (13.5) 197 (15.3) 119 (14.6) 26 (17.9)
Erosive disease (%) - 1,071 (81.6) 682 (83.0) 113 (77.9)
  1. * Except where indicated otherwise, values are the number (%). Among patients with rheumatoid arthritis (RA), 1,288 were evaluated for ever smokers, and 967 were evaluated for anti--cyclic citrullinated peptide antibodies (anti-CCP). Among control subjects, 991 were evaluated for ever smokers. Out of these subjects, 311 cases and 392 controls had been included in a previous study by Cha et al. [20].