Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

Table 1 Baseline patient characteristics of all patients included in the study according to JIA subtype

	Control	Enthesitis related	Extended oligo	Persistent oligo	RF^-poly	RF⁺poly	Psoriatic	All non-sJIA	sJIA
Total (n)	38	33	8	53	58	15	9	176	23
Flow (n)	38	30	5	41	41	15	8	149	14
Expression (n)	29	29	7	38	47	14	8	143	21
Flow and expression (n)	29	26	4	26	30	14	7	107	12
Age at onset (yr)	10.8^a ± 5.3	12.4 ± 2.5	4.7 ± 4.7	5.5 ± 4.0	8.1 ± 5.0	10.8 ± 3.0	7.5 ± 4.2	8.2 ± 4.8	5.6 ± 5.0
Onset to baseline (mo)	N/A	7.1 ± 7.8	5.7 ± 3.3	4.4 ± 3.3	8.1 ± 8.3	5.8 ± 9.3	6.7 ± 7.5	6.4 ± 7.0	3.6 ± 5.9
Female (%)	57.8	15.2	100	67.9	75.9	93.3	66.7	64.2	34.8
WBC in 10⁹/L	N/A	6.7 ± 2.0	8.2 ± 2.3	9.0 ± 3.0	8.5 ± 3.6	8.0 ± 2.3	7.6 ± 1.0	8.2 ± 3.0	18.1 ± 9.6^b
Hgb in g/dl	N/A	13.1 ± 0.9	11.8 ± 0.9	12.2 ± 1.1	12.3 ± 1.1	12.4 ± 1.3	12.5 ± 0.7	12.4 ± 1.1	9.9 ± 1.4^b
Plt in 10⁹/L	N/A	324 ± 76	368 ± 109	369 ± 96	384 ± 152	375 ± 113	370 ± 96	366 ± 117	548 ± 227^b
ESR in mm/h	N/A	15 ± 16	23 ± 17	19 ± 15	23 ± 18	31 ± 24	19 ± 17	21 ± 17	89 ± 40^b
CRP in mg/dl	N/A	1.6 ± 2.2	0.9 ± 1.3	1.2 ± 1.4	1.8 ± 2.8	2.0 ± 2.0	1.0 ± 0.9	1.5 ± 2.1	16.9 ± 14.0^b

^aAge at sampling. ^bP < 0.05 (one-way ANOVA and all multiple pairwise comparisons (Tukey)). Numbers represent mean ± standard deviation, unless otherwise indicated. WBC, white blood cell count; Hgb, hemoglobin; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein.

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