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Table 2 PBMC subpopulations for which significant differences existed between the controls, patients with JIA other than sJIA, and patients with systemic arthritis

From: Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

PBMC subpopulation Percentage of PBMC   Pairwise multiple comparison
  1. Controls 2. non-sJIA 3. sJIA ANOVA 1. vs. 2. 1. vs. 3. 2. vs. 3.
CD3-CD56+ 6.1 ± 3.9 7.4 ± 4.0 4.7 ± 1.7 0.02 NS NS < 0.05
CD56+ dim 5.5 ± 3.5 6.7 ± 3.9 3.7 ± 1.4 0.009 NS NS < 0.05
CD15+CD16- 0.05 ± 0.03 0.06 ± 0.05 0.18 ± 0.19 < 0.001 NS < 0.05 < 0.05
CD8+CD25+ 0.46 ± 0.26 0.78 ± 0.60 0.70 ± 0.40 0.005 < 0.05 NS NS
CD19+ 16.8 ± 6.6 13.2 ± 5.8 11.7 ± 6.6 0.002 < 0.05 < 0.05 NS
CD34+ 0.08 ± 0.04 0.08 ± 0.05 0.16 ± 0.11 < 0.001 NS < 0.05 < 0.05
CD34+CD33- 0.05 ± 0.03 0.06 ± 0.04 0.11 ± 0.09 < 0.001 NS < 0.05 < 0.05
CD34+CD33+ 0.03 ± 0.02 0.02 ± 0.02 0.05 ± 0.03 < 0.001 < 0.05 NS < 0.05
NK bright/dim ratio 0.14 ± 0.09 0.13 ± 0.12 0.28 ± 0.16 < 0.001 NS < 0.05 < 0.05
CD4:CD8 ratio 2.20 ± 0.7 2.14 ± 0.7 2.81 ± 0.9 0.006 NS < 0.05 < 0.05
  1. Differences were analyzed with one-way ANOVA followed by Tukey's pairwise multiple comparison, assuming a significance level of P < 0.05. PBMCs, peripheral blood mononuclear cells; JIA, juvenile idiopathic arthritis; sJIA, systemic JIA; non-sJIA, JIA other than sJIA.