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Table 4 Overlap between erythropoiesis signature and cell-specific signatures

From: Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

Cell type

Probe sets in cell-specific signaturea

Overlap with erythropoiesis signatureb

Overlap observedc

Overlap expectedd

CD4+ T lymphocytes

211

0

0

0.9%

CD8+ T lymphocytes

252

0

0

1.1%

CD14+ monocytes

447

0

0

2.0%

CD19+ B lymphocytes

272

1

2.0%

1.2%

CD56+ NK cells

265

0

0

1.2%

CD33+ myeloid lineage

448

0

0

2.0%

CD34+ stem cells

227

4

8.2%

1.0%

CD105+ mesenchymal stem cells/endothelial precursors

360

18

36.7%

1.6%

CD71+ erythroid precursors

563

39

79.6%

2.5%

BDCA4+ dendritic cells

372

0

0

1.7%

  1. aDetermined by using the HG U133A GeneChip.
  2. bNumber relative to the 49 probe sets from the erythropoiesis signature that are present on the U133A GeneChip.
  3. c(Number of probe sets overlapping with erythropoiesis signature)/(49(total of probe sets in the erythropoiesis signature)) × 100.
  4. d(Number of probe sets in the signature) × (49(total of probe sets in the erythropoiesis signature))/(22,283 total of probe sets on the U133A GeneChip) × 100.