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Table 1 Histological findings of avascular necrosis of the femoral head (ANFH) in Wistar Kyoto rats

From: New insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of gene expression in a rat model

Sex

Treatment

No. of rats

OA/GC

OEL

EO

LO

Male

Placebo

6

2

1

1

1

Male

Prednisone

7

5

1

4

1

Female

Placebo

5

1

0

1

0

Female

Prednisone

12

3

2

1

2

  1. The histological findings of an established (late stage) ANFH were defined as empty lacunae. Early signs of ANFH was considered when apoptosis occurred in more than three osteocytes and/or osteoblasts recognized in a high magnification field (×200); EO, number of early stages of osteonecrosis; LO, number of late stages of osteonecrosis; OA/GC, osteocyte apoptosis and/or ghost cell (a denucleated cell with an unstained center where the nucleus has been); OEL, osteocyte empty lacunae.
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Arthritis Research & Therapy

ISSN: 1478-6362

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