Skip to main content

Table 1 Histological findings of avascular necrosis of the femoral head (ANFH) in Wistar Kyoto rats

From: New insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of gene expression in a rat model

Sex Treatment No. of rats OA/GC OEL EO LO
Male Placebo 6 2 1 1 1
Male Prednisone 7 5 1 4 1
Female Placebo 5 1 0 1 0
Female Prednisone 12 3 2 1 2
  1. The histological findings of an established (late stage) ANFH were defined as empty lacunae. Early signs of ANFH was considered when apoptosis occurred in more than three osteocytes and/or osteoblasts recognized in a high magnification field (×200); EO, number of early stages of osteonecrosis; LO, number of late stages of osteonecrosis; OA/GC, osteocyte apoptosis and/or ghost cell (a denucleated cell with an unstained center where the nucleus has been); OEL, osteocyte empty lacunae.