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Table 1 Characteristics of patients (n = 1,260)

From: Variability over time and correlates of cholesterol and blood pressure in systemic lupus erythematosus: a longitudinal cohort study

Characteristic Number (%) or mean ± SD
Female 1,113 (88.3%)
   Menopausal at entry to studya 224 (20.1%)
   Menopausal during follow-upa 445 (40.0%)
Race: White 880 (73%)
   Black 119 (10%)
   Asian 113 (9%)
   Other 96 (8%)
Age at first clinic visit (years) 35.0 ± 13.6
Disease duration at first clinic visit (years) 4.0 ± 5.0
SLEDAI-2K at first clinic visitb 9.6 ± 7.7
Age at entry to study (years) 35.4 ± 13.7
Disease duration at entry to study (years) 4.4 ± 6.0
SLEDAI-2K at entry to studyb 8.7 ± 7.0
Hypertension at entry to studyc 190 (15.1%)
Hypercholesterolemia at entry to studye 528 (41.9%)
Diabetes at entry to studyf 30 of 1,223 (2.5%)d
Smoker at entry to studyg 247 of 1,235 (20.0%)d
Corticosteroid use at entry to study 763 of 1,257 (60.7%)d
Antimalarial use at entry to studyh 462 of 1,256 (36.8%)d
Immunosuppressive use at entry to studyi 259 of 1,255 (20.6%)d
  1. SD, standard deviation.
  2. aMenopause defined as a minimum of 12 months of amenorrhea, irrespective of cause.
  3. bScores range from 0 to 105, with higher scores indicating more-active disease.
  4. cDiastolic BP ≥ 90 or systolic BP ≥ 140 mm Hg.
  5. dFor these variables, data were incomplete for a small number of patients. The denominator of the fractions in the second column is the total number of patients from whom the percentage was calculated.
  6. eHypercholesterolemia was defined as cholesterol > 5.2 mmol/L.
  7. fDiabetes was defined as fasting plasma glucose > 7.0 mmol/L or diabetes therapy.
  8. gSmoking one or more cigarettes per day.
  9. hAntimalarials include chloroquine and hydroxychloroquine.
  10. iImmunosuppressives include methotrexate, azathioprine, mycophenolate mofetil,
  11. cyclosporine, and cyclophosphamide.