Variablea | Parameter estimate | 95% CI | Pvalue |
|---|
Age (years) | 0.009 | 0.004, 0.014 | 0.0005 |
SLEDAI-2K scoreb | 0.04 | 0.03, 0.05 | < 0.0001 |
Corticosteroids | 0.32 | 0.22, 0.42 | < 0.0001 |
Antimalarialsc | -0.42 | -0.53, -0.32 | < 0.0001 |
Immunosuppressivesd | 0.17 | 0.06, 0.27 | 0.0017 |
Antihypertensivese | 0.19 | 0.08, 0.30 | 0.0009 |
Hypertensionf | 0.34 | 0.22, 0.46 | < 0.0001 |
- GEE, generalized estimating equation; CI, confidence interval.
- aAll variables measured coincident with measurement of total cholesterol.
- bSLE Disease Activity Index 2000; scores range from 0 to 105, with higher scores indicating more-active disease.
- cAntimalarials include chloroquine and hydroxychloroquine.
- d Immunosuppressives include methotrexate, azathioprine, mycophenolate mofetil,
- cyclosporine, and cyclophosphamide.
- eAntihypertensives include all classes of drugs used to lower blood pressure.
- fHypertension is defined as systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mm Hg.
