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Table 6 Independent correlates of total cholesterol in women only, determined by using multivariate linear regression (GEE)

From: Variability over time and correlates of cholesterol and blood pressure in systemic lupus erythematosus: a longitudinal cohort study

Variablea Parameter estimate 95% CI Pvalue
Age (years) 0.009 0.006, 0.011 < 0.0001
SLEDAI-2K scoreb 0.04 0.036, 0.046 < 0.0001
Disease duration (years) -0.004 -0.006, -0.0017 0.0008
Corticosteroids 0.31 0.26, 0.36 < 0.0001
Antimalarialsc -0.41 -0.45, -0.36 < 0.0001
Immunosuppressivesd 0.15 0.11, 0.20 < 0.0001
Antihypertensivese 0.19 0.14, 0.24 < 0.0001
Hypertensionf 0.25 0.19, 0.32 < 0.0001
Lipid-lowering meds (statins) -0.09 -0.15, -0.03 0.004
HRTg 0.17 0.09, 0.25 < 0.0001
  1. GEE, generalized estimating equation; CI, confidence interval.
  2. aAll variables measured coincident with measurement of total cholesterol.
  3. bSLE Disease Activity Index 2000; scores range from 0 to 105, with higher scores indicating more-active disease.
  4. cAntimalarials include chloroquine and hydroxychloroquine.
  5. d Immunosuppressives include methotrexate, azathioprine, mycophenolate mofetil,
  6. cyclosporine, and cyclophosphamide.
  7. eAntihypertensives include all classes of drugs used to lower blood pressure.
  8. fHypertension is defined as systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mm Hg.
  9. gEstrogen with/without progestin hormone-replacement therapy.