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Table 8 Independent correlates of systolic blood pressure in women only, determined by using multivariate linear regression (GEE)

From: Variability over time and correlates of cholesterol and blood pressure in systemic lupus erythematosus: a longitudinal cohort study

Variable Parameter estimate 95% CI Pvalue
Age (years) 0.44 0.40, 0.48 < 0.0001
SLEDAI-2K scorea 0.37 0.30, 0.44 < 0.0001
Antimalarialsb -1.32 -1.96, -0.69 < 0.0001
Immunosuppressivesc -1.81 -2.48, -1.13 < 0.0001
Antihypertensivesd 6.85 6.17, 7.53 < 0.0001
Diabetese 2.43 1.16, 3.70 0.0002
Smokingf 1.12 0.20, 2.04 0.017
Hypercholesterolemiag 3.10 2.41, 3.78 < 0.0001
Lipid-lowering meds (statins) -1.62 -2.52, -0.73 0.0004
  1. GEE, generalized estimating equations; CI, confidence interval.
  2. All variables were measured coincident with measurement of total cholesterol.
  3. aSLE Disease Activity Index 2000; scores range from 0 to 105, with higher scores indicating more-active disease.
  4. bAntimalarials include chloroquine and hydroxychloroquine.
  5. cImmunosuppressives include methotrexate, azathioprine, mycophenolate mofetil,
  6. cyclosporine, and cyclophosphamide.
  7. dAntihypertensives include all classes of drugs used to lower blood pressure.
  8. eDiabetes is defined as fasting plasma glucose > 7.0 mmol/L or diabetes therapy.
  9. fSmoking one or more cigarettes per day.
  10. gHypercholesterolemia defined as total plasma cholesterol > 5.2 mmol/L.