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Table 2 Results of immunohistochemical staining

From: Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis

Number of positive cells (10000 μm2)

SSc (n = 10)

Controls (n = 6)

Pvalue

 

lcSSc (n = 7)

dcSSc (n = 3)

  
 

3.2 ± 0.7

 

> 0.05

CD68

2.9 ± 1.0

3.2 ± 0.4

2.0 ± 0.2

> 0.05

 

3.8 ± 0.8

 

< 0.05*

CD163

4.0 ± 1.1

3.6 ± 0.5

1.2 ± 0.5

< 0.05*

 

3.6 ± 0.6

 

< 0.05*

CD204

3.4 ± 0.7

3.8 ± 0.4

1.4 ± 0.4

< 0.05*

  1. Data are expressed as mean ± standard deviation; P < 0.05*.
  2. The number of CD163+ and CD204+ cells between collagen fibers was significantly greater in SSc patients compared in healthy controls.
  3. dcSSc, diffuse cutaneous systemic sclerosis; lcSSC, limited cutaneous systemic sclerosis; SSC, systemic sclerosis.