| Bivariate (r) | Multivariate (β, r2) | |||||
---|---|---|---|---|---|---|---|
Parameter | Diet | Percentage body fat | Knee OA | Diet (β) | Percentage body fat (β) | Knee OA (β) | Whole model (r2) |
Biomechanical | Â | Â | Â | Â | Â | Â | Â |
   Dark phase locomotion (m) | 0.25 | 0.26 | 0.14 | - | - | - | 0.05 |
   Velocity (cm/s) | -0.42* | -0.40 | 0.01 | 1.02 | -0.11 | 0.14 | 0.21 |
   Prompted velocity (cm/s) | -0.26 | -0.19 | 0.09 | - | - | - | 0.09 |
   Stride frequency (Hz) | -0.34 | -0.37 | 0.08 | - | - | - | 0.22 |
   Prompted stride frequency (Hz) | -0.31 | -0.29 | 0.03 | - | - | - | 0.11 |
   Rotarod latency to fall (s) | -0.71*** | -0.83*** | -0.33 | -18.7 | -10.1** | 0.55 | 0.70*** a |
   Forelimb grip strength (g) | -0.70*** | -0.54* | -0.16 | 15.6** | 0.73 | -0.15 | 0.50** a |
   Hind limb grip strength (g) | -0.45* | -0.46* | -0.26 | - | - | - | 0.21 |
Neurobehavioral | Â | Â | Â | Â | Â | Â | Â |
   Hotplate withdrawal latency (s) | -0.63** | -0.55** | -0.31 | 2.24 | 0.076 | -0.106 | 0.43* |
   Tail-flick withdrawal latency (s) | -0.02 | -0.01 | -0.13 | - | - | - | 0.02 |
   Time in open areas (%total)b | -0.47* | -0.46** | 0.01 | 2.56 | -0.18 | 0.18 | 0.43* |
   Time freezing (%total)b | 0.46* | 0.32 | 0.33 | -14.06* | -1.16 | 0.95 | 0.35* |
   Stretch attendsb | -0.66*** | -0.60** | -0.20 | 4.85 | -0.03 | -0.03 | 0.51** a |
   Open-closed transitionsb | -0.18 | -0.17 | 0.32 | - | - | - | 0.23 |
   Time immobilec (s) | -0.56** | -0.44 | -0.30 | 63.1* | 4.0 | -3.34 | 0.37 |
Inflammatory | Â | Â | Â | Â | Â | Â | Â |
   IL-1α | -0.08 | -0.09 | -0.49* | 18.8 | 3.0 | -8.2* | 0.27 |
   IL-1 receptor antagonist | -0.05 | -0.07 | -0.18 | - | - | - | 0.03 |
   IL-12 | 0.18 | 0.17 | 0.19 | - | - | - | 0.06 |
   Keratinocyte-derived cytokine | 0.17 | 0.17 | -0.21 | - | - | - | 0.12 |
   IFNγ-induced protein | 0.10 | -0.01 | 0.06 | - | - | - | 0.08 |
   MIP-1α | 0.24 | 0.39 | 0.17 | - | - | - | 0.22 |
   Leptin | 0.84*** | 0.95*** | 0.53** | -1.9 | 2.9*** | 1.1* | 0.93*** a |
   Adiponectin | -0.19 | -0.02 | -0.40 | 2694* | 324* | -274** | 0.42* |