Figure 2From: Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by iloprost infusionValidation of gene array results by Real Time RT-PCR. Genes selected for validation by Real Time RT-PCR in CECs before (bar 1) and after (bar 2) iloprost infusion in SSc patients without (panel A) and with (panel B) digital ulcers. ICAM-1, Bcl2 and VEGF transcripts were increased several times after iloprost infusion in both groups of patients. The increase was statistically significant (P < 0.05) in all cases. The experiments were carried out in triplicates.Back to article page