Skip to main content

Advertisement

Table 2 Comparison of absolute and relative Cr metabolite levels between FM patients and healthy controls

From: Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate

Metabolite location Healthy group FM group Pvalue
Posterior cingulate gyrus
Glx 9.89 ± 1.04 10.71 ± 0.50 0.049
Glx/Cr 1.72 ± 0.23 1.90 ± 0.12 0.034
Left hippocampus
Ins 6.09 ± 0.78 4.91 ± 0.85 0.004
Ins/Cr 1.22 ± 0.07 1.09 ± 0.08 0.002
Cho 1.72 ± 0.20 1.47 ± 0.22 0.019
NAA+NAAG 7.05 ± 0.64 6.27 ± 0.89 0.034
Right hippocampus
Ins 5.17 ± 0.62 4.49 ± 0.74 0.008
Sensorimotor cortex    
Ins/Cr 0.84 ± 0.07 0.76 ± 0.09 0.05
  1. Values are expressed as the mean ± SD (in arbitrary institutional units).
  2. Cho, choline; Cr, creatine; FM, fibromyalgia; Glx, glutamate+glutamine; Glx/Cr, glutamate+glutamine/creatine ratio; Ins, myoinositol; Ins/Cr, myoinositol/creatine ratio; NAA+NAAG, N-acetylaspartate + N-acetylaspartyl glutamate.