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Table 2 Comparison of absolute and relative Cr metabolite levels between FM patients and healthy controls

From: Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate

Metabolite location

Healthy group

FM group

Pvalue

Posterior cingulate gyrus

Glx

9.89 ± 1.04

10.71 ± 0.50

0.049

Glx/Cr

1.72 ± 0.23

1.90 ± 0.12

0.034

Left hippocampus

Ins

6.09 ± 0.78

4.91 ± 0.85

0.004

Ins/Cr

1.22 ± 0.07

1.09 ± 0.08

0.002

Cho

1.72 ± 0.20

1.47 ± 0.22

0.019

NAA+NAAG

7.05 ± 0.64

6.27 ± 0.89

0.034

Right hippocampus

Ins

5.17 ± 0.62

4.49 ± 0.74

0.008

Sensorimotor cortex

   

Ins/Cr

0.84 ± 0.07

0.76 ± 0.09

0.05

  1. Values are expressed as the mean ± SD (in arbitrary institutional units).
  2. Cho, choline; Cr, creatine; FM, fibromyalgia; Glx, glutamate+glutamine; Glx/Cr, glutamate+glutamine/creatine ratio; Ins, myoinositol; Ins/Cr, myoinositol/creatine ratio; NAA+NAAG, N-acetylaspartate + N-acetylaspartyl glutamate.