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Table 3 Correlations between brain metabolites that show significant differences between both groups and psychological variables

From: Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate

Metabolite HADS-anx HADS-dep PVAS Sphigm MMSE Catastroph FIQ
Posterior cingulate gyrus Glx
(Coefficient) 0.43 0.44 0.37 -0.45 0.39 0.40 0.45
(P value) 0.057 0.047a 0.107 -0.047a 0.089 0.081 0.043a
Posterior cingulate gyrus Glx/Cr ratio
(Coefficient) 0.42 0.47 0.39 -0.50 0.36 0.40 0.55
(P value) 0.062 0.034a 0.08 -0.024a 0.117 0.077 0.011a
  1. aP < 0.05.
  2. Catastroph, Pain catastrophization scale; FIQ, Fibromyalgia Impact Questionnaire; Glx, glutamate+glutamine; Glx/Cr, glutamate+glutamine/creatine ratio; HADS-Anx, Hospital Anxiety Depression Scale, subscale anxiety; HADS-Dep, Hospital Anxiety Depression Scale, subscale depression; MMSE, Mini Mental State Examination; PVAS, Pain Visual Analogue Scale; Sphigm, pain threshold assessed by sphygmomanometer (the pressure that is needed to evoke pain).