Figure 3

T cell production of IFNγ, IL-2 and TGFβ following incubation with pDCs alone and pDCs + apoPMNs. (a1) and (b1) Autologous T cells that had been incubated with either healthy donor (n = 30) or SLE (n = 30) pDCs alone or pDCs + apoPMNs did not produce Th1 related cytokines IFNγ and IL-2. (a2) and (b2) Allogeneous T cells that had been incubated with either HD (n = 30) or SLE (n = 30) pDCs + apoPMNs produced IFNγ and IL-2. (c) Autologous and allogeneous T cells that had been incubated with either HD (n = 30) pDCs alone or pDCs + apoPMNs produced low levels of Treg related TGFβ though the difference did not reach statistical significance. Values are expressed in Median (interquartile range, range). auto-T, autologous T cells; allo-T, allogenous T cells; pDCs + apoPMNs, pDCs that had been loaded with apoptotic polymorphonuclear cells; HD, healthy donors.