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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Maintenance of cytomegalovirus-specific CD4pos T-cell response in rheumatoid arthritis patients receiving anti-tumor necrosis factor treatments

Figure 1

Representative flow-cytometry profiles of the intracellular interferon (IFN)-γ response in CD4pos T cells from patients receiving anti-TNF treatments. Peripheral blood mononuclear cells (PBMCs) from two cytomegalovirus (CMV)-seropositive patients (a, b) were incubated with CMV Ags (CMV) and control Ags (CT), and intracellular IFN-γ production was measured with flow cytometry, as indicated in Materials and Methods. Responses from CMV-seronegative patients (c) are shown as controls. CD4pos T-cell responses are represented as the percentage of IFN-γpos cells within the CD4pos population.

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