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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis

Figure 2

Dose-dependence of liposomal DxM-P in adjuvant arthritis (Experiment 4). (a-c): Dose-response of treatment with liposomal DxM-P (3 × 1 mg/kg, 3 × 0.1 mg/kg, or 3 × 0.01 mg/kg); all groups were normalized to the same mean value for each parameter on Day 14 (n = 6 each). + P ≤ 0.05, ++ P ≤ 0.01 vs. AA/PBS; $ P ≤ 0.05, $$ P ≤ 0.01 vs. AA/DxM-P-liposomes 0.01 mg/kg; § P ≤ 0.05, §§ P ≤ 0.01 vs. AA/DxM-P-liposomes 0.1 mg/kg, * P ≤ 0.05 vs. AA/DxM-P 1 mg/kg; all Mann Whitney U-test. ↑ administration of PBS or liposomal DxM-P.

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