Figure 1
From: Bone events and evolution of biologic markers in Gaucher disease before and during treatment
Time until the first bone event (BE) in the 62 Gaucher-disease patients receiving enzyme-replacement therapy (ERT). The dashed grey lines represent the 95% CI of the survival curve. (a) Between diagnosis and first ERT during the first 30 years of follow-up. (b) Between first ERT and closing date (for treated patients) during 15 years of follow-up. No. at risk is the number of patient followed at the indicated time; No. with BE is the number of patients who had a BE. Twenty-one patients had BE before ERT and 10 under ERT during each follow-up period.