Skip to main content

Table 3 Endothelial biomarkers and markers of inflammation in patients with early RA and age- and sex-matched healthy controls

From: Atherosclerosis in early rheumatoid arthritis: very early endothelial activation and rapid progression of intima media thickness

 

RA (n= 79)

Controls (n= 44)

sVCAM-1, ng/mL

742.7 (237.9) (*)

631.4 (173.2)

sICAM-1, ng/mL

354.1 (131.8)*

290.6 (66.9)

sE-selectin, ng/mL

51.8 (19.2)

53.8 (16.7)

sL-selectin, ng/mL

1252.0 (306.2)

1279.7 (273.2)

MCP-1, pg/mL

1945.6 (936.9)***

1125.1 (475.5)

PAI-1, μg/L

64.1 (37.3)

59.1 (28.7)

tPA-mass, μg/L

7.17 (3.04)

8.06 (4.32)

VWF, %

203.1 (74.1)*

161.8 (61.2)

ESR, mm/h

18.6 (16.7)

---

CRP, mg/L

13.6 (13.9)

---

DAS28

3.62 (1.4)

---

HAQ

0.65 (0.6)

---

  1. Data is given as mean value (standard deviation).
  2. (*) = 0.059, * P < 0.05, ** P < 0.01, *** P < 0.001.
  3. CRP, C-reactive protein; DAS28, disease activity score; ESR, erythrocyte sedimentation rate; MCP-1, monocyte chemotactic protein-1; HAQ, health assessment questionnaire; PAI-1, plasminogen activator inhibitor-1; tPA, tissue plasminogen activator; RA, rheumatoid arthritis; sICAM-1, soluble intercellular adhesion molecule-1; sVCAM-1, soluble vascular cell adhesion molecule-1; VWF, VonWillebrand factor.