Skip to main content

Table 4 Simple linear regression models of associations between some of the traditional risk factors for CVD, markers of inflammation and endothelial biomarkers and IMT or ED-FMD in 79 patients with early RA

From: Atherosclerosis in early rheumatoid arthritis: very early endothelial activation and rapid progression of intima media thickness

 

IMT

ED-FMD

 

β

P

β

P

Sex, female

-1.02/+

0.005

3.82/+

0.002

Age

0.001/year

<0.001

- 0.178/year

<0.001

Systolic BP

0.030/mmHg

0.001

 

ns

Cholesterol

0.004/mmol L-1

0.027

 

ns

Smoking, years

0.029/year

0.005

 

ns

Snuff, years

0.043/year

0.027

 

ns

PAI-1

 

ns

-0.026/μg L-1

0.064

tPA-mass

73.0/μg L-1

0.005

 

ns

VWF

5.914/%

0.003

 

ns

sL-selectin

-1.058/ng mL-1

0.026

4.961/ng mL-1

0.004

MCP-1

4.650/pg mL-1

0.002

 

ns

  1. Not significant after adjustment for sex and/or age.
  2. BP, blood pressure; CVD, cardiovascular disease; ED-FMD, endothelial dependent flow mediated dilatation; IMT, intima media thickness; MCP-1, monocyte chemotactic protein-1; ns, Not significant; PAI-1, plasminogen activator inhibitor-1; RA, rheumatoid arthritis; tPA, tissue plasminogen activator; VWF, VonWillebrand factor.