| | |
Function
|
Pain
|
Pt global estimate
|
Fatigue
|
PtGA
|
|---|
|
Percent work time missed
|
Better
|
4.2 (19.0)‡
|
1.5 (7.2)
|
2.0 (7.7)†
|
3.9 (15.8)‡
|
1.6 (7.1)
|
| |
Worse
|
15.5 (31.5)
|
16.3 (34.0)
|
15.6 (33.9)
|
14.5 (32.4)
|
16.9 (34.6)
|
| |
Effect size
|
0.46
|
0.61
|
0.55
|
0.43
|
0.63
|
|
Percent impairment while working
|
Better
|
14.5 (18.8)
|
11.6 (15.0)
|
10.9 (13.1)
|
12.8 (16.8)
|
11.7 (14.3)
|
| |
Worse
|
39.1 (20.1)
|
39.6 (21.1)
|
40.0 (21.7)
|
38.7 (21.0)
|
41.2 (21.0)
|
| |
Effect size
|
1.27
|
1.56
|
1.66
|
1.38
|
1.69
|
|
Percent overall work impairment
|
Better
|
17.6 (24.8)
|
12.2 (16.7)
|
11.8 (15.7)
|
14.8 (22.1)
|
12.3 (16.1)
|
| |
Worse
|
46.5 (28.2)
|
47.4 (30.0)
|
47.2 (30.3)
|
46.0 (28.9)
|
48.9 (30.1)
|
| |
Effect size
|
1.10
|
1.46
|
1.48
|
1.22
|
1.55
|
|
Percent activity impairment
|
Better
|
19.0 (21.1)
|
15.7 (17.0)
|
15.1 (17.0)
|
19.6 (21.0)
|
17.5 (19.0)
|
| |
Worse
|
52.7 (23.3)
|
51.9 (24.4)
|
52.0 (23.7)
|
49.9 (25.6)
|
51.9 (24.5)
|
| |
Effect size
|
1.53
|
1.73
|
1.79
|
1.30
|
1.58
|
- Pt global estimate, patient global estimate on health impact; PtGA, patient global assessment of disease activity
- If not indicated, t test P values <0.001; †, t test P values <0.01; ‡, t test P values <0.05
- Better status, ≤median; Worse status, >median. The median for each health status outcome was shown in Table 1
