|
4 = Mostly hyaline cartilage
|
1 = <25% of the calcified cartilage layer intact
|
1 = Not bonded
|
|
3 = Mostly fibrocartilage
|
2 = 25-49% of the calcified cartilage layer intact
|
2 = Bonded at one end/partially both ends
|
|
2 = Mostly noncartilage
|
3 = 50-75% of the calcified cartilage layer intact
|
3 = Bonded at both sides
|
|
1 = Exclusively noncartilage
|
4 = 76-90% of the calcified cartilage layer intact
|
Basal integration of implanted material (Basl)
|
|
Matrix staining (Matx)
|
5 = Complete intactness of the calcified cartilage layer
|
1 = <50%
|
|
1 = None
|
Subchondral bone formation (Bform)
|
2 = 50-70%
|
|
2 = Slight
|
1 = No formation
|
3 = 70-90%
|
|
3 = Moderate
|
2 = Slight
|
4 = 91-100%
|
|
4 = Strong
|
3 = Strong
|
Inflammation (InfH)
|
|
Structural integrity (Stru)
|
Histologic appraisal of surface architecture (SurfH)
|
1 = Strong inflammation
|
|
1 = Severe disintegration
|
1 = Severe fibrillation
|
3 = Slight inflammation
|
|
2 = Cysts or disruption
|
2 = Moderate fibrillation
|
5 = No inflammation
|
|
3 = No organization of chondrocytes
|
3 = Slight fibrillation or irregularity
|
Histologic grading system (Hgtot)
|
|
4 = Beginning of columnar organization of chondrocytes
|
4 = Normal
|
Some of the histologic variables:
|
|
5 = Normal, similar to healthy mature cartilage
|
Histologic appraisal defect filling (FilH)
|
Tissue morphology (Ti)
|
|
Chondrocytes clustering in implant (Clus)
|
1 = <25%
|
Matrix staining (Matx)
|
|
1 = 25-100% of cells clustered
|
2 = 26-50%
|
Structural integrity (Stru)
|
|
2 = <25% of the cells clustered
|
3 = 51-75%
|
Cluster formation (Clus)
|
|
3 = No clusters
|
4 = 76-90%
|
Tidemark opening (Tide)
|
| |
5 = 91-110%
|
Bone formation (Bform)
|
| | |
Histologic surface architecture (SurfH)
|
| | |
Histologic degree of defect filling (FilH)
|
| | |
Lateral integration of defect-filling tissue (Basl) and histologic signs of inflammation (InfH)
|
