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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

Figure 5

Time course of trabecular bone volume fraction. Mice were scanned every 3 weeks in an in vivo micro-CT scanner. (a and b) Patella, (b and c) epiphysis, (d and e) metaphysis. (a, c and e) Sham and OVX groups. aP < 0.05 for OVX+IA versus Sham+Sal; bP < 0.05 for OVX+IA versus Sham+IA, both according to unpaired t-test. dP < 0.05 for OVX+Sal versus Sham+Sal according to unpaired t-test. (b, d and f) OVX and OVX+E groups. eP < 0.05 for OVX+IA versus OVX+E+IA; fP < 0.05 for OVX+Sal versus OVX+E+Sal, both according to unpaired t-test. Note that OVX+Sal and OVX+IA curves are overlapping in (e) and (f).

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