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Table 1 Presence of osteophytes on histology and micro-CT

From: Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

  Patella Medial Tibia
  Histology Micro-CT Histology Micro-CT
Sham+Sal 1/8 a 0/8 b 2/8 g 0/8 h
Sham+IA 6/8 a 5/8 b 8/8 g 5/8 h
OVX+Sal 2/7 0/7 c 6/7 0/7 i
OVX+IA 7/7 7/7 c,f 7/7 7/7 i,j
OVX+E+Sal 0/4 d 0/4 1/4 0/4
OVX+E+IA 4/4 d 2/4 4/4 0/4 j
OVX+BP+Sal 0/8 e 0/8 7/8 0/8 k
OVX+BP+IA 5/8 e 1/8 f 8/8 6/8 k
  1. Osteophyte presence was scored on histology and in micro-CT data sets of the patellae and tibiae and are presented as the number of patellae/tibiae in which an osteophyte was visible on histology or micro-CT. Identical italic character indicates significant difference between these conditions according to Fisher's exact test. CT = computed tomography; Sham = sham ovariectomy; Sal = saline injection; IA = iodoacetate injection; OVX = ovariectomy; E = oestrogen supplementation; BP = bisphosphonate treatment.