| Patella | Medial Tibia |
---|
 | Histology | Micro-CT | Histology | Micro-CT |
---|
Sham+Sal | 1/8 a | 0/8 b | 2/8 g | 0/8 h |
Sham+IA | 6/8 a | 5/8 b | 8/8 g | 5/8 h |
OVX+Sal | 2/7 | 0/7 c | 6/7 | 0/7 i |
OVX+IA | 7/7 | 7/7 c,f | 7/7 | 7/7 i,j |
OVX+E+Sal | 0/4 d | 0/4 | 1/4 | 0/4 |
OVX+E+IA | 4/4 d | 2/4 | 4/4 | 0/4 j |
OVX+BP+Sal | 0/8 e | 0/8 | 7/8 | 0/8 k |
OVX+BP+IA | 5/8 e | 1/8 f | 8/8 | 6/8 k |
- Osteophyte presence was scored on histology and in micro-CT data sets of the patellae and tibiae and are presented as the number of patellae/tibiae in which an osteophyte was visible on histology or micro-CT. Identical italic character indicates significant difference between these conditions according to Fisher's exact test. CT = computed tomography; Sham = sham ovariectomy; Sal = saline injection; IA = iodoacetate injection; OVX = ovariectomy; E = oestrogen supplementation; BP = bisphosphonate treatment.