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Table 1 Presence of osteophytes on histology and micro-CT

From: Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

 

Patella

Medial Tibia

 

Histology

Micro-CT

Histology

Micro-CT

Sham+Sal

1/8 a

0/8 b

2/8 g

0/8 h

Sham+IA

6/8 a

5/8 b

8/8 g

5/8 h

OVX+Sal

2/7

0/7 c

6/7

0/7 i

OVX+IA

7/7

7/7 c,f

7/7

7/7 i,j

OVX+E+Sal

0/4 d

0/4

1/4

0/4

OVX+E+IA

4/4 d

2/4

4/4

0/4 j

OVX+BP+Sal

0/8 e

0/8

7/8

0/8 k

OVX+BP+IA

5/8 e

1/8 f

8/8

6/8 k

  1. Osteophyte presence was scored on histology and in micro-CT data sets of the patellae and tibiae and are presented as the number of patellae/tibiae in which an osteophyte was visible on histology or micro-CT. Identical italic character indicates significant difference between these conditions according to Fisher's exact test. CT = computed tomography; Sham = sham ovariectomy; Sal = saline injection; IA = iodoacetate injection; OVX = ovariectomy; E = oestrogen supplementation; BP = bisphosphonate treatment.