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Table 4 Test of independence and gene-gene interactions

From: Prediction model for knee osteoarthritis based on genetic and clinical information

Interaction P value
  Case-controla Case-onlyb Two modelsc
ASPN × GDF5 0.598 0.273 0.056
GDF5 × DVWA 0.416 0.701 0.920
DVWA × ASPN 0.197 0.104 0.290
  1. a, bP values based on χ2 association test to 3 × 3 tables by genotype model. cANOVA for two logistic regression models, with or without interactions. ASPN, aspirin; DVWA, double von Willebrand factor A domain; GDF5, growth differentiation factor 5.