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Table 4 Test of independence and gene-gene interactions

From: Prediction model for knee osteoarthritis based on genetic and clinical information

Interaction

P value

 

Case-controla

Case-onlyb

Two modelsc

ASPN × GDF5

0.598

0.273

0.056

GDF5 × DVWA

0.416

0.701

0.920

DVWA × ASPN

0.197

0.104

0.290

  1. a, bP values based on χ2 association test to 3 × 3 tables by genotype model. cANOVA for two logistic regression models, with or without interactions. ASPN, aspirin; DVWA, double von Willebrand factor A domain; GDF5, growth differentiation factor 5.