Table 2 Quantitative trait loci (QTL) associated with osteoarthritis
From: Genetic markers of osteoarticular disorders: facts and hopes
| Region | |||
|---|---|---|---|
| Reference | QTL | affected | Phenotype |
| [28] | 8q | GOA | Early-onset OA-CPDD (1 family) |
| [29] | 2q23?35 | Hand | Nodal OA |
| [30] | 11q | Hip, knee | Female OA |
| [31] | 2q | Hip, knee | OA of the hip |
| 4q | Female OA of the hip | ||
| 6p/6q | OA of the hip | ||
| 11q | Female OA | ||
| 16p/16q | Female OA of the hip | ||
| [32] | 2q12?13 | Hand | Distal interphalangeal joint OA |
| 4q26?27 | Distal interphalangeal joint OA | ||
| 7p15?21 | Distal interphalangeal joint OA | ||
| X-cen | Distal interphalangeal joint OA | ||
| [33] | 4q35 | Hip | Premature degenerative OA of the hip |
| [34] | 6q12-13 | Hip, knee | Female OA of the hip |
| 6p21.3 | Female OA of the hip | ||
| [35] | 2q31 | Hip, knee | Familial OA of the hip |