From: Genetic markers of osteoarticular disorders: facts and hopes
Genetic | Association | ||
---|---|---|---|
polymorphism | Phenotype | found? | Reference |
VDR | Female knee OA | Yes | [42] |
Knee OA (osteophytosis) | Yes | [41] | |
Female OA (hip replacement) | No | [50] | |
Hand, hip, knee OA | No | [51] | |
Idiopathic OA | No | [39] | |
COL2A1 | PGOA/chondrodysplasia | Yes | [140] |
Nodal GOA | No | [141] | |
GOA, finger joints OA | No | [24] | |
GOA | Yes | [45] | |
Female OA (hip replacement) | No | [50] | |
GOA | Yes | [46] | |
Knee OA (joint space narrowing) | Yes | [47] | |
COL1A1 | Female OA (hip replacement) | No | [50] |
Idiopathic female OA | Yes | [39] | |
ER a | GOA | Yes | [38] |
Idiopathic OA | No | [39] | |
TGFB1 | Spine OA (osteophytosis) | Yes | [48] |
IGF-I | GOA | Yes | [44] |
Aggrecan proteoglycan | Male bilateral hand OA | Yes | [49] |