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Table 1 Demographic and laboratory data by disease

From: Disease-specific definitions of vitamin D deficiency need to be established in autoimmune and non-autoimmune chronic diseases: a retrospective comparison of three chronic diseases

 

SLE

RA

T2DM

P-value

 

n = 123

n = 100

n = 3691

 

Age, years Median (IQR)

34.5 (26.7, 47.7)

60.5 (52.6, 66.8)

63.3 (53.7, 71.7)

<0.001

Gender (% female)

109 (89)

88 (88)

2,686 (73)

<0.001

Race/Ethnicity (%)

    

   African-American

46 (39)

32 (34)

1,252 (36)

 

   Hispanic

39 (33)

42 (45)

1,176 (34)

0.199

   Other

34 (29)

20 (21)

1,046 (30)

 

   Unknown

14 (12%)

16 (16%)

217 (6%)

 

25OHD, ng/ml

    

Median (IQR)

18.0 (11.3, 25.4)

20.9 (16.1, 29.9)

16.8 (11.1, 24.2)

0.0001

Season (%)

    

   April-September

61 (50)

50 (50)

1,698 (46)

0.47

Serum creatinine >1.5 mg/dl (%)

16 (13)

2(2)

855 (27)

<0.001

Serum calcium, mg/dl

    

Median (IQR)

9.2 (8.9, 9.5)

9.5 (9.1, 9.7)

9.6 (9.2, 10)

0.001

Bisphosphonates use (%)

20 (16)

34 (34)

346 (9)

<0.001

Calcium supplementation (%)

60 (49)

59 (59)

864 (23)

<0.001

Prednisone use (%)

85 (69)

65 (65)

231 (6)

<0.001

Vitamin D supplementation (%)

57 (46)

56 (56)

867 (23)

<0.0001

  1. SLE, systemic lupus erythematosus; RA, rheumatoid arthritis; T2DM, type 2 diabetes mellitus; 25OHD, 25hydroxyvitamin D; IQR, inter-quartile range.