Figure 2From: Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritisVery early rheumatoid arthritis (VERA) patients and synovial fluid (SF) of established rheumatoid arthritis (RA) display increased levels of interleukin-17A (IL-17A). (a) The serum concentration of IL-17A was measured in VERA and very early arthritis (VEA) patients as well as healthy controls and patients with established RA. The serum concentration of IL-17A was increased in VERA patients compared with healthy controls. (b) The concentration of IL-17A was measured in the SF collected from patients with established RA and from a control group with osteoarthritis (OA). In the SF of patients with RA, we observed a significant increase of IL-17A. Dotted lines represent the limit of detection for the assay. Differences were considered statistically significant for P values of less than 0.05 according to the Mann-Whitney test.Back to article page