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Table 2 Cytokine levels in healthy controls and patients with VERA, VEA, established RA, or OA

From: Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis

Cytokine, pg/mL

Controls

VERA

VEA

RA

RA SF

OA SF

IL-1β

4.2

(4.2-116.8)

17.7

(4.2-99.7)

4.2

(4.2-272.7)

4.2

(4.2-360.3)

6.5

(4.2-322.1)

4.2

(4.2-15.5)

IL-6

1.2

(1.2-7.2)

5.2

(1.2-153.2)

1.2

(1.2-84.7)

8.2

(1.2-19.7)

6361.0

(272.7-24,135.0)

177.6

(46.6-4,881.0)

IL-8

9.9

(0.5-407.7)

57.6

(12.5-1,546.0)

8.9

(0.5-665.2)

15.2

(0.8-67.5)

735.7

(28.3-3,717.0)

48.2

(22.0-680.0)

IL-17A

2.5

(2.5-333.7)

62.0

(2.5-1,714.0)

2.5

(2.5-1,477.0)

2.6

(2.5-375.6)

21.1

(2.5-369.1)

2.5

(2.5-9.5)

IL-22

43.3

(43.3-153.4)

165.3

(43.3-380.6)

43.3

(43.3-270.5)

131.7

(75.8-250.7)

153.4

(75.8-336.0)

151.7

(92.4-235.3)

  1. Values are presented as median (range). IL, interleukin; OA, osteoarthritis; RA, rheumatoid arthritis; SF, synovial fluid; VEA, very early arthritis; VERA, very early rheumatoid arthritis.