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Table 2 Cytokine levels in healthy controls and patients with VERA, VEA, established RA, or OA

From: Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis

Cytokine, pg/mL Controls VERA VEA RA RA SF OA SF
IL-1β 4.2
(4.2-116.8)
17.7
(4.2-99.7)
4.2
(4.2-272.7)
4.2
(4.2-360.3)
6.5
(4.2-322.1)
4.2
(4.2-15.5)
IL-6 1.2
(1.2-7.2)
5.2
(1.2-153.2)
1.2
(1.2-84.7)
8.2
(1.2-19.7)
6361.0
(272.7-24,135.0)
177.6
(46.6-4,881.0)
IL-8 9.9
(0.5-407.7)
57.6
(12.5-1,546.0)
8.9
(0.5-665.2)
15.2
(0.8-67.5)
735.7
(28.3-3,717.0)
48.2
(22.0-680.0)
IL-17A 2.5
(2.5-333.7)
62.0
(2.5-1,714.0)
2.5
(2.5-1,477.0)
2.6
(2.5-375.6)
21.1
(2.5-369.1)
2.5
(2.5-9.5)
IL-22 43.3
(43.3-153.4)
165.3
(43.3-380.6)
43.3
(43.3-270.5)
131.7
(75.8-250.7)
153.4
(75.8-336.0)
151.7
(92.4-235.3)
  1. Values are presented as median (range). IL, interleukin; OA, osteoarthritis; RA, rheumatoid arthritis; SF, synovial fluid; VEA, very early arthritis; VERA, very early rheumatoid arthritis.