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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease

Figure 4

Effect of anti-GM-CSF treatment on cytokine levels in the joints. GM-CSF, TNFa and IL-1? levels were measured by enzyme-linked immunosorbent assay in washouts from ankle joints of arthritic mice for mice treated with anti-GM-CSF or control mAb every second day from days 21 to 31 post immunization. Results are expressed as the mean level ? SEM (pg/ml). *P = 0.02 and **P = 0.007 compared with control mAb-treated mice. GM-CSF, Granulocyte macrophage-colony stimulating factor; IL-1?, interleukin-1?; mAb, monoclonal antibody; TNFa, tumor necrosis factor-a.

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