Figure 6
Tumor growth after transplantation of monocytic EPCs in the in vivo tumor neovascularization model. Tumors from colon carcinoma CT-26 cells injected subcutaneously into the back of mice alone or in combination with monocytic EPCs (104 or 105) derived from SSc patients or healthy controls. Tumor growth was assessed 10 days later. (a) Representative subcutaneous tumors from mice that received transplanted CT-26 cells alone, or CT-26 cells along with monocytic EPCs (104 or 105) from a healthy control or an SSc patient. (b) Tumor volumes in mice that received transplants of CT-26 cells alone, or CT-26 cells in combination with monocytic EPCs from SSc patients or healthy controls (104 or 105). Results are shown as the mean and standard deviation.