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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits

Figure 5

Synovial MSCs affect gene profile of nucleus pulposus cells in co-culture system. (a) Morphology of mono-culture of rat nucleus pulposus cells and human synovial MSCs at seven days, and co-culture of rat nucleus pulposus cells with human synovial MSCs at one and seven days. (b) Human gene profile of human synovial MSCs in mono-culture and in co-culture with rat nucleus pulposus cells. (c) Rat gene profile of rat nucleus pulposus cells in mono-culture and in co-culture with human MSCs. (d) Number of altered rat genes seven days after co-culture of rat nucleus pulposus cells with human synovial cells by duplicate of microarray analyses.

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