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Table 1 Characteristics of rheumatoid arthritis study patientsa

From: Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione s-transferasein a cross-sectional study

 

Mean (SD) or number (%)

 

VARA

(n= 703)

SONORA

(n= 610)

Sociodemographics

  

   Age, yrb

64 (11)

53 (15)

   Male genderb

655 (93%)

173 (28%)

ACPA-positiveb

536 (76%)

420 (69%)

RA risk factors

  

   HLA-DRB1 SE-positive

531 (76%)

434 (71%)

   One copy

356 (51%)

303 (50%)

   Two copies

175 (25%)

131 (21%)

   GSTM1-null

372 (53%)

315 (52%)

Smoking historyb

(n = 693)

(n = 610)

   Never

140 (20%)

213 (35%)

   Former

371 (54%)

257 (42%)

   Current

182 (26%)

141 (23%)

  1. aACPA, anticitrullinated protein antibody; GSTM1, glutathione S-transferase Mu-1; SE, shared epitope; SONORA, Study of New-Onset RA; VARA, Veterans Affairs Rheumatoid Arthritis Registry. bP < 0.05 for differences between VARA and SONORA.