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Table 1 Characteristics of rheumatoid arthritis study patientsa

From: Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione s-transferasein a cross-sectional study

  Mean (SD) or number (%)
  VARA (n= 703) SONORA (n= 610)
Sociodemographics   
   Age, yrb 64 (11) 53 (15)
   Male genderb 655 (93%) 173 (28%)
ACPA-positiveb 536 (76%) 420 (69%)
RA risk factors   
   HLA-DRB1 SE-positive 531 (76%) 434 (71%)
   One copy 356 (51%) 303 (50%)
   Two copies 175 (25%) 131 (21%)
   GSTM1-null 372 (53%) 315 (52%)
Smoking historyb (n = 693) (n = 610)
   Never 140 (20%) 213 (35%)
   Former 371 (54%) 257 (42%)
   Current 182 (26%) 141 (23%)
  1. aACPA, anticitrullinated protein antibody; GSTM1, glutathione S-transferase Mu-1; SE, shared epitope; SONORA, Study of New-Onset RA; VARA, Veterans Affairs Rheumatoid Arthritis Registry. bP < 0.05 for differences between VARA and SONORA.