Skip to main content

Table 3 Comparison between SLE patients with and without atherosclerotic plaques

From: Increased prevalence of vulnerable atherosclerotic plaques and low levels of natural IgM antibodies against phosphorylcholine in patients with systemic lupus erythematosus

 

SLE patients

 

With plaque

(n= 49)

Without plaque

(n= 62)

P

Age, years

55.79 ± 9.23

41.7 ± 12.76

< 0.001

Disease duration, mean

14.00 years

9.82 years

0.025

Current smokers, % (no.)

7.2% (n = 8)

6.3% (n = 7)

0.44

Presence of hypertension,% (no.)

31.5% (n = 35)

27% (n = 30)

0.014

Presence of diabetes,% (no.)

4.5% (n = 5)

0.9% (n = 1)

0.047

HOMA IR

1.41 (0.91 to 1.94)

1.20 (0.73 to 1.94)

0.41

Glucos (mmol/L)

4.70 (4.30 to 5.00)

4.35 (3.90 to 4.70)

0.0013

LDL(mmol/L)

2.87 ± 1.05

2.28 ± 0.66

0.001

Hyperlipidemia (LDL > 3)

38.77 (n = 19)

19.35 (n = 12)

0.023

Kolesterol (mmol/L)

5.05 ± 1.26

4.35 ± 0.98

0.001

ApoB/ApoA1, median

0.60 (0.50 to 0.80)

0.50 (0.45 to 0.60)

0.004

High sensitivity CRP, mg/l

1.85 (0.82 to 4.05)

1.75 (0.69 to 4.8)

0.980

Triglicerides (mmol/L)

1.00 (0.74 to 1.50)

0.94 (0.61 to 1.30)

0.065

BMI (kg/m2)

25.95 (22.28 to 28.41)

24.16 (20.08 to 26.84)

0.032

SLAM

6.00 (5 to 9)

6.50 (4 to 10)

0.41

SLEDAI

2 (0 to 5)

2 (0 to 6)

0.46

SLICC

1 (0 to 4)

1(0 to 2)

0.39

Lupus anticoagulans

10.81% (n = 12)

14.41% (n = 16)

0.87

Anticardiolipin Ab

8.18% (n = 9)

11.81% (n = 13)

0.70

Beta 2 glycoprotein 1

15.45% (n = 17)

18.18% (n = 20)

0.83

Cumulative lifetime glukocorticoid dose/year (g/year)

2.49 (1.75 to 3.68)

2.59 (1.87 to 3.49)

0.952

Glucocorticoid last year, gram

0.9 (0 to 2.19)

1.8 (0.07 to 2.70)

0.093

Chloroquin/hydroxychlorochine

42.85% (n = 21)

54.83% (n = 34)

P = 0.210

IgM antiPC

48.75 (25.79 to 104.78)

85.94 (50.02 to 231.52)

P = 0.001

IgM antiPC < = 10th percentile (%)

23.40

10.17

0.0651

IgM antiPC < = 25th percentile (%)

40.43

23.73

0.0651

IgM antiPC < = 33th percentile (%)

57.45

28.81

0.0030

  1. anti-PC, antibodies against PC; CR, C-reactive protein; HDL, high density lipoprotein; HOMA, homeostasis model assessment of insulin resistance; LDL, low density lipoprotein; PC, phosphorylcholine; SLAM, Systemic Lupus Activity Measure; SLEDAI, Systemic Lupus Erythematosus diseases activity index; SLICC, Systemic Lupus International Collaborating Clinics damage index.