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Table 1 Main characteristics (means and confidence intervals or percentages) of study population by gender

From: Vitamin D deficiency in rheumatoid arthritis: prevalence, determinants and associations with disease activity and disability

 

RA-women (N= 1,014)

RA-men (N= 177)

P1

Controls (N= 1,019)

P2

 

Mean

95% C.I.

Mean

95% C.I.

 

Mean

95% C.I.

 

Age (years)

58.7

58.0 to 59.4

60.0

58.4 to 61.6

n.s.

58.9

58.1 to 59.7

n.s.

BMI (kg/m2)

25.0

24.7 to 25.3

25.9

25.4 to 26.5

0.01

25.7

25.5 to 26.0

0.002

Disease duration (mo.)

138

131 to 145

138

119 to 157

n.s

   

Swollen joint count (range 0 to 28)

3.12

2.81 to 3.43

1.98

1.53 to 2.43

0.003

   

DAS 28

3.96

3.90 to 4.03

3.55

3.40 to 3.70

<0.001

   

HAQ score (range 0 to 3)

1.18

1.13 to 1.24

0.87

0.75 to 0.99

<0.001

   

ADL (range 4 to 16)

8.41

3.02 to 8.22

7.24

6.85 to 7.63

<0.001

   

25(OH)D (ng/ml)

24.0

23.2 to 25.0

24.7

22.9 to 26.6

n.s.

19.3

18.4 to 20.2

<0.001

PTH (pg/ml)

25.0

24.1 to 25.9

24.9

23.2 to 26.6

n.s.

33.1

31.7 to 34.3

<0.001

Pre-menopause

35.7%

   

33.2%

ns

Sun exposure time >30 minutes

33.5%

51.4%

0.01

35%

ns

Smoking

20.8%

20.3%

n.s.

16.3%

<0.001

Extra-articular manifestations

15.3%

13.6%

n.s.

  

Steinbrocker Functional state >1

66.8%

58.2%

n.s.

  

DMARDs therapy

88.0%

89.3%

n.s.

  

Anti to TNF therapy

46.5%

39.5%

n.s.

  

ACR Remission

22.9%

24.9%

n.s.

  

Good treatment response

43.7%

46.9%

n.s.

  

Osteoporosis therapy

29.6%

13.6%

<0.01

  

Glucocorticoid therapy

86.5%

83.1%

n.s.

  

Rheumatoid Factor positive

63.3%

66.3%

n.s.

  

Anti CCP positive

66.3%

66.7%

n.s.

  
  1. Abbreviations: 25(OH)D, 25-hydroxyvitamin D; ACR, American College of Rheumatology; ADL, activities of daily living; Anti-CCP, anti Cyclic Citrullinated Peptide; Anti-TNF, tumor necrosis factor α blocker; BMI, body mass index; CRP, C-reactive protein; DAS 28, Disease Activity Score 28; DMARDs, disease modifying antirheumatic drugs; HAQ, Health Assessment Questionnaire Disability Index; PTH, parathyroid hormone; RA, rheumatoid arthritis.
  2. p1 is referred to between gender differences and p2 to between female patients and control women; n.s. = not significant.