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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Pathogenic effect of interleukin-17A in induction of Sjögren's syndrome-like disease using adenovirus-mediated gene transfer

Figure 5

Stimulated saliva flow in treated C57BL/6J mice. One week prior to salivary gland cannulations with either Ad5-LacZ or Ad5-IL17A vector, stimulated saliva volumes were determined for individual mice within each of the four experimental groups: early treatment with Ad5-LacZ (n = 10) or Ad5-IL17A (n = 11) at 7 wks of age (a) or late treatment with Ad5-LacZ (n = 10) or Ad5-IL17A (n = 8) at 16 wks of age (b). Saliva was collected every three to five weeks post-treatment until the mice were euthanized. Statistical analysis was used to determine the significance between the Ad5-LacZ and Ad5-IL17A treated mice at each time point. (NS: not significant, P = *< 0.05, P = **< 0.01, P = ***< 0.001). Arrows indicate the initial time point of vector cannulation.

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