The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis

Table 1 Camptothecin does not affect fibroblast viability

Confluent fibroblasts after 48 h treatment with indicated doses of CPT were trypsinized and cell number was the mean of two counts using a Coulter counter. Values are mean cell numbers ± SEM from five SSc and healthy control pairs after treatment with CPT. CPT = camptothecin; NS, normal fibroblasts; SD, SSc fibroblasts.

ISSN: 1478-6362