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Table 1 Camptothecin does not affect fibroblast viability

From: The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis

  Cell number
CPT concentration (mol/l) NS SD
None (controls) 5904 ± 731 5928 ± 1081
10-9 5614 ± 818 6166 ± 1120
10-8 5424 ± 720 5368 ± 1046
10-7 5051 ± 770 5785 ± 1203
10-6 5142 ± 801 5711 ± 1351
  1. Confluent fibroblasts after 48 h treatment with indicated doses of CPT were trypsinized and cell number was the mean of two counts using a Coulter counter. Values are mean cell numbers ± SEM from five SSc and healthy control pairs after treatment with CPT. CPT = camptothecin; NS, normal fibroblasts; SD, SSc fibroblasts.