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Table 2 Relationship between baseline BMLs and increasing BMLs with baseline demographic factors*

From: Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults

  Univariate OR (95% CI) P Multivariable OR (95% CI)† P
Absence/Presence of BML at baseline     
   Age 1.00 (0.82, 1.22) 0.992 0.99 (0.80, 1.21) 0.905
   Male sex 1.61 (1.08, 2.41) 0.020 1.70 (1.13, 2.56) 0.011
   BMI 1.31 (1.07, 1.61) 0.009 1.34 (1.09, 1.65) 0.005
BML increase at any site**     
   Age 1.10 (0.86, 1.40) 0.463 1.08 (0.84, 1.39) 0.529
   Male sex 1.74 (1.05, 2.86) 0.030 1.78 (1.07, 2.95) 0.026
   BMI 1.19 (0.94, 1.51) 0.146 1.23 (0.97, 1.58) 0.093
  1. *Values are per one standard deviation increase in respective variable (except sex).
  2. OR, odds ratio; 95% CI, 95% confidence interval; BMI, body mass index; BMLs, bone marrow lesions
  3. **No increase or incident BML versus an increase or incident BML at any site (medial tibial, medial femoral, lateral tibial, and/or lateral femoral)
  4. †Adjusted for sex and BMI in the age model, age and BMI in the sex model, or age and sex in the BMI model.
  5. Boldface denotes statistically significant result.