Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults

Table 2 Relationship between baseline BMLs and increasing BMLs with baseline demographic factors*

	Univariate OR (95% CI)	P	Multivariable OR (95% CI)†	P
Absence/Presence of BML at baseline
Age	1.00 (0.82, 1.22)	0.992	0.99 (0.80, 1.21)	0.905
Male sex	1.61 (1.08, 2.41)	0.020	1.70 (1.13, 2.56)	0.011
BMI	1.31 (1.07, 1.61)	0.009	1.34 (1.09, 1.65)	0.005
BML increase at any site**
Age	1.10 (0.86, 1.40)	0.463	1.08 (0.84, 1.39)	0.529
Male sex	1.74 (1.05, 2.86)	0.030	1.78 (1.07, 2.95)	0.026
BMI	1.19 (0.94, 1.51)	0.146	1.23 (0.97, 1.58)	0.093

*Values are per one standard deviation increase in respective variable (except sex).
OR, odds ratio; 95% CI, 95% confidence interval; BMI, body mass index; BMLs, bone marrow lesions
**No increase or incident BML versus an increase or incident BML at any site (medial tibial, medial femoral, lateral tibial, and/or lateral femoral)
†Adjusted for sex and BMI in the age model, age and BMI in the sex model, or age and sex in the BMI model.
Boldface denotes statistically significant result.

ISSN: 1478-6362