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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model

Figure 1

Increased arthritis severity in Mmp8 -deficient mice. (a) Clinical score measured in 10 Mmp8-/- mice, 10 Mmp8+/+ mice and 10 Mmp8+/- mice after intraperitoneal injection of 200 μl K/BxN mice serum at days 0 and 2. Values expressed as mean ± standard error of the mean (SEM); P = 0.025, by analysis of covariance (ANCOVA) test. (b) Clinical score measured in 17 Mmp8-/- mice and 17 Mmp8+ mice after intraperitoneal injection of 100 μl K/BxN mice serum at days 0 and 2. Values expressed as mean ± SEM; P = 0.04, by ANCOVA test.

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