MMP levels in supernatants from human articular chondrocytes stimulated with recombinant human chemerin21-157. Cell supernatants were assessed for content of MMPs after 24 h of stimulation with 10 nM or 100 nM recombinant chemerin21-157. The levels of MMP-1 (a), MMP-2 (b), MMP-3 (c), MMP-8 (d), and MMP-13 (e) are shown as mean ± standard error of the mean values. Results are from six separate experiments analyzed in duplicates. Concentration is given relative to amount of protein (μg/ml). *P < 0.05, stimulated versus unstimulated.