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Table 1 Characteristics of the study subjects

From: Association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis

 

No stratification

Stratified ± ROA at examination A

References

 

n= 141 (100%)

-ROA, n= 63 (45%)

+OA, n= 78 (55%)

n= 17 (100%)

Men

116 (82%)

49 (78%)

67 (86%)

15 (88%)

Age at examination A, years

51 (31-73)

51 (32-73)

52 (31-73)

54 (37-70)

BMI at examination A, kg/m2

26 (18-41)

26 (18-35)

27 (21-41)

26 (20-31)

Years between index surgery and examination A

18 (15-22)

18 (15-22)

18 (15-22)

Na

Years between examinations A and B

7.5 (4.0-10.4)

7.1 (4.0-10.1)

7.8 (4.0-10.4)

8.6 (8.6-8.8)

ROA at examination A

78 (55%)

0 (0%)

78 (100%)

1 (6%)

ROA at examination B

106 (75%)

28 (44%)

78 (100%)

1 (6%)

End-stage OA at examination B

31 (22%)

2 (3.2%)

29 (37%)

0 (0)

Arthroplasty or osteotomy at examination B

2 (1.4%)a

0 (0)

2 (2.6%)a

0 (0)

Loss of joint space/Progression of the JSN score

76 (54%)

22 (35%)

54 (69%)

2 (12%)

Progression of osteophytes

66 (47%)

21 (33%)

45 (58%)

2 (12%)

Progression of ROA

98 (70%)

35 (56%)

63 (81%)

4 (24%)

SF ARGS at examination A, pmol ARGS/ml

6.95 (0.15-15.07)

6.96 (0.15-14.58)

6.94 (0.31-15.07)

Nd

SF ARGS at examination B, pmol ARGS/ml

Nd

Nd

Nd

7.19 (3.63-12.72)

  1. aOne arthroplasty and one osteotomy. Na, not applicable; Nd, not determined. Values are expressed as numbers (%) or mean (range). BMI, body mass index; JSN, joint space narrowing; OA, osteoarthritis; ROA, radiographic OA.