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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases

Figure 2

Numerical chromosomal aberrations in the OA synovial membrane. Bars as in Fig. 1 (means ± SEM for n = 10–16 patients). Polysomies (hatched bars) in OA synovial tissue only exceeded threshold levels (broken lines) in the case of chromosome 7, except for a very marginal increase for chromosome 8. In P-1 synovial FB, polysomies for chromosomes 4 and 7 and monosomy 18 were above threshold levels; in P-4 synovial FB, polysomies for chromosomes 4, 6, 7, 8, and 9 were above threshold levels. Considering only trisomic nuclei (shaded bars), numerical chromosomal aberrations were observed for chromosome 7 only, except for a limited elevation of trisomy 8 in P-4 synovial FB. P-0 = primary culture; P-1 = passage 1; P-4 = passage 4.

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