Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases

Supplementary Table 4 Structural chromosomal aberrations in osteoarthritis

	Karyotype
	Peripheral	Synovial fibroblasts		Skin fibroblasts
	blood
Chromosome	lymphocytes	Passage 1	Passage 4	Passage 1	Passage 4
1	46,XX,del(1)(q23),+mar[1]	46,XX,chrb(1)(q23)[1]t(3;7)(q23;q34),-21,(Collagenase digest)			46,XX,del(1)(q11 or q12)[1]
		48,XX,+del(1),+7,+9[1]
		46,XX,chrb(1)(q12)[2] (Collagenase digest)
		46,X,-X,+7, chrb(1)(q12)[1]
2	46,XX,t(2;10)(q14;q22)[1]
5		46,XX,del(5)(p13)[1]	46,XX,t(5;11)(q23;q12)[1]
7	46,XX,t(7;12)(p14;q13)[1]	46,XY,del(7)(q32)[1]
	47,XX,+del(7) (q11.1→ qter)[1]	46,XX,-2,+4,-6,-8,+15,+add(7)(p22)[1]
8			46,XY,-4,+7,t(8;11) (p11.2;p11.2)[1]
9	46,XX,del(9)(q11)[2]	46,XX,chrb(9)(q13)[1]
	46,XX,chrb(9)(q21)[1]
11	45,X-X,-10,inv(11) (p15.5;q23.3),+mar[1]	46,XX,t(11;15)[1] (Collagenase-digest)
12		46,XX,chrb(12q?13)[1] (Collagenase-digest)
16	46,XY,fra(16)(q22.1)[2]

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