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Table 1 Information on patients and subjects included in the study

From: Salivary glands of primary Sjögren's syndrome patients express factors vital for plasma cell survival

 

Patient/Subject Nr.

Focus score

GC+/-

Age

Gender

Salivary secretion

Ro/SSA

La/SSB

ANA

RF

IgG

IgA

IgM

pSS

1

1

-

48

F

2.0

-

-

0.36

<16

10.0

2.3

1.3

pSS

2

1

-

50

F

1.6

nt

nt

nt

nt

nt

nt

nt

pSS

3

1

+

72

F

1.9

nt

nt

nt

nt

nt

nt

nt

pSS

4

1

-

50

F

1.1

-

-

0.57

<11

10.1

1.2

0.9

pSS

5

1

-

48

F

0.2

-

-

0.68

<11

10.7

0.8

0.9

pSS

6

1

+

62

F

1.7

+

-

2.20

<11

13.9

1.8

3.0

pSS

7

1

-

48

F

0.7

+

-

6.91

nt

19.4

4.1

0.5

pSS

8

1

-

37

F

0.5

-

-

4.55

<11

15.9

3.1

1.7

pSS

9

1

-

68

F

0.8

-

-

2.00

<16

9.8

2.2

0.6

pSS

10

4

-

54

F

0.1

+

-

4.77

32

15.1

4.4

0.9

pSS

11

2

-

58

F

2.5

-

-

0.60

nt**

12.4

1.5

1.3

pSS

12

3

+

40

F

0.2

+

+

nt

nt

nt

nt

nt

pSS

13

4

+

52

F

1.0

-

-

0.17

nt**

12.4

2.7

1.1

pSS

14

12

+

46

F

0

-

-

0.66

nt**

11.9

2.4

1.7

pSS

15

4

-

72

M

0.2

+

+

6.05

nt

16.6

3.7

0.9

pSS

16

4

+

60

F

0.1

-

-

8.05

<11

8.0

1.4

2.1

pSS

17

4

-

56

F

1.2

-

-

0.29

<11

7.1

0.9

1.5

pSS

18

2

-

56

F

0.5

-

-

-*

<11

9.1

0.7

1.8

pSS

19

2

-

50

F

0.8

+

+

1.27

nt**

nt

nt

nt

pSS

20

4

-

58

M

1.5

+

+

9.72

<16

22.1

1.7

0.9

pSS

21

6

+

59

F

4.6

+

+

+*

224**

19.8

1.5

1.4

CIG

22

0

-

46

F

0.9

-

-

0.39

<11

9.0

2.0

0.7

CIG

23

0

-

66

F

4.5

+

-

0.77

<11

19.2

6.4

0.5

CIG

24

0

-

49

F

0.8

-

-

0.1

<11

9.9

1.8

1.0

CIG

25

0

-

70

F

0.9

-

-

0.39

nt

nt

nt

nt

CIG

26

0

-

54

F

1.0

-

-

0.12

<11

14.1

2.0

0.5

NG

27

0

-

54

F

0.2

-

-

0.28

<11

8.8

1.1

0.4

NG

28

0

-

58

F

1.0

-

-

0.45

<11

9.6

1.6

0.8

NG

29

0

-

54

F

2.1

-

-

0.41

nt

nt

nt

nt

NG

30

0

-

55

F

0

nt

nt

nt

nt

nt

nt

nt

  1. CIG, chronically inflamed glands; NG, normal glands; pSS, primary Sjögren's syndrome. Focus score: the number of focal infiltrates of more than 50 mononuclear cells per 4 mm2. GC+/-: presence or absence of germinal center like structures based on morphology of the infiltrates. Age, age at the time of SS diagnosis. Gender, Female/Male. Saliva secretion, Mean un-stimulated whole saliva secretion per 15 minutes, normal values ≤1.5 ml/15 minutes. Ro-SSA and La-SSB autoantibodies in serum, positive or negative. ANA, Antinuclear antibodies in serum: negative < 0.99, grey zone 1.00 to 1.65 and positive >1.65. * From 2009 measure as positive or negative. RF, rheumatoid factor in serum: <11 or <16 negative, 32 uncertain. ** Patients with highly positive cyclic citrullinated peptide antibody (CCP). Immunoglobulin levels in serum, normal values: IgG 6.0 to 15.3 g/L, IgA 1.0 to 4.1 g/L and IgM 0.5 to 2.5 g/L. nt, not tested.